2,099 research outputs found
Machinery Early Fault Detection Based on Dirichlet Process Mixture Model
© 2013 IEEE. The most commonly used single feature-based anomaly detection method for the complex machinery, such as large wind power equipment, steam turbine generator sets, and reciprocating compressors, exhibits a defect of low-alarm accuracy due to the non-stationary characteristic of the vibration signals. In order to improve the accuracy of fault detection, a novel method based on the Dirichlet process mixture model (DPMM) is proposed. First, the features of the mechanical vibration signals are used to construct the feature space of the equipment. The DPMM modeling method is then applied to self-learn the probabilistic mixture model of the feature space. The normal working condition model is used as the benchmark model. The early fault detection is realized by using a precise difference measurement method based on Kullback-Leibler divergence to calculate the difference between the real-time model and the benchmark model accurately, and by comparing the calculation result with a self-learned alarm threshold. The effectiveness and the adaptability of this novel early fault detection method are verified by comparing it to the single feature-based anomaly detection method and the Gaussian mixture model (GMM)-based early fault detection method
Climate and soil moisture content during development ofthe frst palaeosol in the southern Loess Plateau
The scientific problems concerning Quaternary soil water content and the water cycle have not been researched. This study examined the soil water content and depth of distribution of gravitational water in the south Loess Plateau during development of the first palaeosol layer (S1) by methods such as field investigation, electron microscopy, energy spectrum analysis, chemical analysis, and so on. The purpose was to reveal the climate, water balance and vegetation type at the time when S1 developed. The depth of migration of CaCO3 and Sr were 4.2 m below the upper boundary of the S1 palaeosol, and the depth of weathered loess beneath the argillic horizon was 4.0 m. Ferri‐argillans developed well in the argillic horizon and their depth of migration was 1 m below the argillic horizon. These findings suggest that the climate during the last interglacial was subtropical and humid, and the soil‐water balance was positive. Gravitational water was present to a depth of least 4.2 m from the top of S1, and the water content was adequate for tree growth. The chemical weathering index showed that this palaeosol has been moderately weathered
Effects of pulsed anodic oxide on the intermixing in InGaAs/GaAs and LnGaAs/AlGaAs quantum wells
Intermixing in InGaAs/AlGaAs quantum well structures was studied with and without an anodic oxide cap by rapid thermal annealing. Blueshifts in the photoluminescence (PL) energy were observed. Anodic oxide was demonstrated to suppress the blueshift noticeably. The suppression of the blueshift was attributed to a strain reduction.published_or_final_versio
Simulation of multilevel cell spin transfer switching in a full-Heusler alloy spin-valve nanopillar
Author name used in this publication: Shi, S. Q.2012-2013 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
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Local structure adaptability through multi cations for oxygen redox accommodation in Li-Rich layered oxides
Stable lattice oxygen redox (l-OR) is the key enabler for achieving attainable high energy density in Li-rich layered oxide cathode materials for Li-ion batteries. However, the unique local structure response to oxygen redox in these materials, resulting in energy inefficiency and hysteresis, still remains elusive, preventing their potential applications. By combining the state-of-the-art neutron pair distribution function with crystal orbital overlap analysis, we directly observe the distinct local structure adaption originated from the potential O–O chemical bonds. The structure adaptability is optimized based on the nature of multi transition metals in our model compound Li1.2Ni0.13Mn0.54Co0.13O2, which accommodates the oxygen redox and at the same time preserves the global layered structure. These findings not only advance the understanding of l-OR, but also provide new perspectives in the rational design of high-energy-density cathode materials with reversible and stable l-OR
Observation of a ppb mass threshoud enhancement in \psi^\prime\to\pi^+\pi^-J/\psi(J/\psi\to\gamma p\bar{p}) decay
The decay channel
is studied using a sample of events collected
by the BESIII experiment at BEPCII. A strong enhancement at threshold is
observed in the invariant mass spectrum. The enhancement can be fit
with an -wave Breit-Wigner resonance function with a resulting peak mass of
and a
narrow width that is at the 90% confidence level.
These results are consistent with published BESII results. These mass and width
values do not match with those of any known meson resonance.Comment: 5 pages, 3 figures, submitted to Chinese Physics
Selection of Saccharomyces cerevisiae strains for efficient very high gravity bio-ethanol fermentation processes
An optimized very high gravity (VHG)
glucose medium supplemented with low cost nutrient
sources was used to evaluate bio-ethanol production
by 11 Saccharomyces cerevisiae strains. The industrial
strains PE-2 and CA1185 exhibited the best
overall fermentation performance, producing an ethanol
titre of 19.2% (v/v) corresponding to a batch
productivity of 2.5 g l-1 h-1, while the best laboratory
strain (CEN.PK 113-7D) produced 17.5% (v/v)
ethanol with a productivity of 1.7 g l-1 h-1. The
results presented here emphasize the biodiversity
found within S. cerevisiae species and that naturally
adapted strains, such as PE-2 and CA1185, are likely
to play a key role in facilitating the transition from
laboratory technological breakthroughs to industrialscale
bio-ethanol fermentations.Fundação para a Ciência e a Tecnologia (FCT) - PTDC/BIO/66151/2006, SFRH/
BD/64776/2009, SFRH/BPD/44328/
200
MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput. New software solutions are needed to allow efficient comparative analysis of multiple models in the context of multiple cellular objectives. Here, we present the user-friendly software framework Multi-Metabolic Evaluator (MultiMetEval), built upon SurreyFBA, which allows the user to compose collections of metabolic models that together can be subjected to flux balance analysis. Additionally, MultiMetEval implements functionalities for multi-objective analysis by calculating the Pareto front between two cellular objectives. Using a previously generated dataset of 38 actinobacterial genome-scale metabolic models, we show how these approaches can lead to exciting novel insights. Firstly, after incorporating several pathways for the biosynthesis of natural products into each of these models, comparative flux balance analysis predicted that species like Streptomyces that harbour the highest diversity of secondary metabolite biosynthetic gene clusters in their genomes do not necessarily have the metabolic network topology most suitable for compound overproduction. Secondly, multi-objective analysis of biomass production and natural product biosynthesis in these actinobacteria shows that the well-studied occurrence of discrete metabolic switches during the change of cellular objectives is inherent to their metabolic network architecture. Comparative and multi-objective modelling can lead to insights that could not be obtained by normal flux balance analyses. MultiMetEval provides a powerful platform that makes these analyses straightforward for biologists. Sources and binaries of MultiMetEval are freely available from https://github.com/PiotrZakrzewski/MetEval/downloads
Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension
Pulmonary hypertension remains a major clinical problem despite current therapies. In this study, we examine for the first time a novel pharmacological target, smooth muscle myosin, and determine if the smooth muscle myosin inhibitor, CK-2019165 (CK-165) ameliorates pulmonary hypertension.Six domestic female pigs were surgically instrumented to measure pulmonary blood flow and systemic and pulmonary vascular dynamics. Pulmonary hypertension was induced by hypoxia, or infusion of the thromboxane analog (U-46619, 0.1 µg/kg/min, i.v.). In rats, chronic pulmonary hypertension was induced by monocrotaline.CK-165 (4 mg/kg, i.v.) reduced pulmonary vascular resistance by 22±3 and 28±6% from baseline in hypoxia and thromboxane pig models, respectively (p<0.01 and 0.01), while mean arterial pressure also fell and heart rate rose slightly. When CK-165 was delivered via inhalation in the hypoxia model, pulmonary vascular resistance fell by 17±6% (p<0.05) while mean arterial pressure and heart rate were unchanged. In the monocrotaline model of chronic pulmonary hypertension, inhaled CK-165 resulted in a similar (18.0±3.8%) reduction in right ventricular systolic pressure as compared with sildenafil (20.3±4.5%).Inhibition of smooth muscle myosin may be a novel therapeutic target for treatment of pulmonary hypertension
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